Aspartame
sweetener · 1 unit dose (~40mg pure aspartame)
Aspartame scores 2 on the Healthy Body Index, with its clearest signal on mTOR↓.
2
HBI score · Depleting
Why it scores low
- Its strongest longevity signal is mTOR↓ (4/10), backed by AMPK.
- HBI uses best-of-top-3 scoring, so aspartame is credited for the pathways it excels at.
Dimension breakdown
0–100 per dimensionLongevity
AMPK · NRF2
20
Micronutrient
density
0
Phytochemical
ORAC
0
Anti-inflammatory
DII
30
Gut microbiome
prebiotic
0
Cardiovascular
K:Na
40
Longevity pathway activation
0–10 per pathwayAMPK
AMPK
1.0
NRF2
NRF2
0.0
AUTOPHAGY
Autophagy
1.0
SIRT
Sirtuin
1.0
mTOR↓
mTOR
4.0
SENO
Senolytic activity
0.0
NAD+
NAD+
0.0
TELO
Telomere
1.0
HBI uses best-of-top-3 scoring — a food is judged on the pathways it excels at, not diluted by the ones it doesn’t touch.
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